Corneal Endothelial Damage Following FS-LASIK Combined with Corneal Cross-Linking Surgery: Case Report With Literature Review

Purpose: To report a case of early corneal endothelial damage in a patient with high myopia after undergoing FS-LASIK combined with corneal cross-linking. Case Description: An observational case report of an 18-year-old male patient with high myopia who underwent FS-LASIK combined with corneal cross-linking. On the third day postoperatively, slit lamp examination revealed corneal edema in the right eye, small pit-like lesions on the endothelial surface of both eyes, and a significant drop in endothelial cell count and percentage of hexagonal cells compared to preoperative levels. One week postoperatively, corneal edema in the right eye and small pits on the endothelial surface of both eyes disappeared, and the number and area of dark spots significantly reduced. At two months postoperatively, the visual acuity of both eyes was 20/20 , and the dark spots on the endothelial surface disappeared, the corneal endothelial cell count, the percentage of hexagonal cells, and the coefficient of variation in cell size returned to preoperative levels. Conclusion: We report a case of early, reversible endothelial damage following FS-LASIK combined with corneal cross-linking.