Simulation of optical coherence tomography to determine refractive indices of retinal layers in different organisms

Optical coherence tomography (OCT) is a non-invasive imaging technique capable to produce two-dimensional (2D) images or three-dimensional (3D) reconstructions of inhomogeneous samples. OCT is mainly used in ophthalmology as a powerful tool for early diagnosis of eye diseases. The main goal of this article is to simulate the interferogram of OCT images and obtain the refractive index related to each retina layers in different organisms, including human, monkey, cow and dog. To achieve this goal, by simulating the interferogram of OCT images in the time and frequency domains for a supergaussian light source, different retinal samples are studied and for the given layer thicknesses, the refractive indices of different retina layers are determined.