Multi-resistant ST 258 Klebsiella pneumoniae presenting a hypermucoviscous phenotype

To characterize phenotypically and genotypically a strain of Klebsiella pneumoniae ST258 isolated from an immunosuppressed patient treated at a University Hospital in Brazil, it was performed Antimicrobial Susceptibility Testing, Analysis of the Ability to form Biofilm, Genome Sequencing and String Test. The sample was characterized as a non-biofilm-forming, multi-resistant and hypermucoviscous strain. Genomic analysis revealed the presence of resistance genes, virulence genes and plasmids. This is the first report of hypervirulent hypermucoviscous KPC ST258 in Rio de Janeiro, Brazil. KPC ST258 represents a significant global health threat due to the limited available treatment to fight these infections. This observation poses a threat to the community and hospital environments, highlighting the need for increased surveillance to detect these strains.