Monofocal intraocular lenses with enhanced intermediate function provide more satisfaction in phaco-vitrectomy for the epiretinal membrane and cataracts

A newly developed monofocal intraocular lens (IOL), known as Eyhance, features a continuously increasing refractive power from the periphery to the center of the lens, aiming to enhance intermediate vision. Our multicenter prospective, nonrandomized, comparative study in Japan aimed to compare the outcomes of phaco-vitrectomy for epiretinal membrane (ERM) and cataracts using Eyhance (DIB00V) versus a conventional monofocal intraocular lens (DCB00V). Sixty-two eyes implanted with Tecnis-1 and 79 eyes with Eyhance were analyzed. While there was no significant improvement in distance-corrected intermediate visual acuity with Eyhance (0.35 in logMAR) compared to DCB00V (0.39 in logMAR, p  = 0.200), Rasch analysis of patient-reported outcomes using the Japanese modified Catquest-9SF Questionnaire revealed that Eyhance scored higher in patient general satisfaction ( p  = 0.0269). Subgroup analysis revealed a trend toward better postoperative distance-corrected intermediate visual acuity in patients with a certain degree of postoperative myopia. In conclusion, Eyhance may not provide superior immediate vision in phaco-vitrectomy for ERM compared to the conventional monofocal IOL, but it is not inferior. Furthermore, Eyhance could enhance postoperative satisfaction in patients with ERM and cataracts.