Molecular characteristics of human respiratory syncytial virus infection: an outbreak in children in 2023, Beijing, China
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A resurgent outbreak of children respiratory syncytial virus (RSV) infection occurred on April 2023, Beijing. To elucidate the dominant genotypes and molecular characteristics of RSV isolates, totally 11 partial G gene sequences were obtained. Six RSVA and five RSVB isolates were clustered into ON1 and BA9 genotypes. Amino acid substitutions T113I, V131D, H258Q, and H266L were co-occurrences in four RSVA isolates. One strain had a substitution to S174N in T cell epitope of RSVA G protein. In RSVB G protein, P237L, P247T, K258N/S, H259Y, T266I, N296Y, T302I, and E305K were newly found but not in our previous study.
