Trends in Subtypes of and Risk Factors for Stroke in Tianjin, China, 2005-2020

Objective A more detailed understanding of stroke is essential for the implementation of effective prevention strategies and mitigation of the disease burden. The aim of our study was to examine the temporal trends in age- and sex-specific risk factors for stroke subtypes in Tianjin. Methods We retrospectively analyzed stroke data from 2005 to 2020. The trend in the proportion of people hospitalized and age- and sex-specific risk factors were evaluated using linear regression analysis. Results Overall, the proportion of AIS (acute ischemic stroke, AIS) showed an upward trend from 64% in 2005 to 80% in 2020, while ICH (intracerebral hemorrhage, ICH) and SAH (subaraclmoid hemorrhage, SAH) showed a downward trend from 26.7% and 15.05% in 2005 to 9.2% and 5.03% in 2020, respectively ( p  < 0.001). The average age of onset of AIS showed a downward trend from 63.45 years in 2005 to 62.99 years in 2020 ( p  < 0.001). The trend change was mainly attributed to male patients, the average age of whom decreased from 61.96 in 2005 to 61.49 years in 2020 ( p  = 0.02). Based on age correlation analysis, people with a cumulative incidence of AIS tended to be younger. Stroke combined with both hypertension and diabetes showed an upward trend for different stroke subtypes, especially AIS and ICH. Conclusions In 2005–2020, the average age of onset of stroke in Tianjin, China, was younger. There was a trend toward a younger age, a greater proportion of young people with incident cases and male sex and a trend toward increased common risk factors for stroke. This is of great public health importance because additional interventions for common risk factors are necessary to prevent stroke, particularly in certain populations.