Lifestyle and Bone Health: Analyzing the Association Between LE8 Scores and BMD

Purpose This study aims to investigate the association between Life's Essential 8 scores(LE8) and bone mineral density(BMD) in adults aged 20–59 years. Methods This cross-sectional study utilized nationally representative data from NHANES 2011–2018. Weighted multiple linear regression models were used to explore the relationship between LE8 scores and different levels of cardiovascular health(CVH) with BMD. Additionally, subgroup analyses were conducted to examine the differences in the impact of LE8 scores on BMD across different age groups, genders, races, socioeconomic statuses, and BMI. Results A total of 2,159 participants were included in the study. After adjusting for all covariates, LE8 scores were significantly and positively linearly associated with lumbar spine BMD, thoracic spine BMD, trunk BMD, and total BMD ( P  < 0.05). Compared to the low CVH group, individuals in the medium and high CVH groups had higher BMD ( P  < 0.05). Subgroup analyses revealed that this relationship was more pronounced in the 20–35 age group and within the normal BMI range ( P  < 0.05). In females, thoracic spine BMD was more sensitive to changes in LE8 scores ( P  < 0.05). Conclusion This study reveals a positive linear relationship between LE8 and BMD. Higher LE8 scores are associated with greater BMD in adults aged 20–59 years, suggesting that lifestyle interventions can effectively prevent and treat OP.