Antioxidant activity and myco-chemical profiling of Campylospora parvula Kuzuha isolated from the roots of Rubus ellipticus

Endophytic fungi are important sources of various bioactive natural compounds. Present work elucidates the antioxidant activity and chemical characterization of Campylospora parvula Kuzuha isolated from the roots of ethno medicinal plant Rubus ellipticus . Antioxidant activities were tested using DPPH, MCA and FRAP assays, total phenolic and flavonoid content by Folin-Ciocalteu and aluminum chloride method, respectively. Chemical profile of ethyl acetate extract was illustrated by using Gas chromatography and mass spectrometry (GC-MS) analysis. The ethyl acetate extract of C. parvula presents IC50, 47.75±3.6 µg/ml for DPPH, 53.36±2.6 µg/ml for MCA and 360.54±8.6 AAE/g dry extract for FRAP assay. GCMS analysis revealed the presence of Octanal, 2-(phenylmethylene)- (16.24%), 1-(4-Iopropylphenyl)-2-methylpropyl acetate (12.91%), Benzoic acid, 2-hydroxy-, phenylmethyl ester (11.85%) as major compounds. Findings of the present study are promising and keenly hopeful for further research on individual compound to assess their potential, especially in the pharmacology sector.