Diagnostic aspect of ferritin level in acquired heart failure in children: a retrospective study in Covid-19 patients

Background More important than the issue of Covid is the management of its consequences on other vital organs. Many biomarkers change as a result of this respiratory infection, which depends on the function of vital organs such as the heart. This study aims to investigate the relationship between serum ferritin level and acquired heart diseases in children suffered from covid. Method This retrospective study started by examining ferritin levels measured in children with a positive PCR result. Children who underwent echocardiography from March 2019 to one year later were examined. We evaluated the age, gender, echocardiography results and ferritin level of these children. Results Out of a total of 116 examined covid patients, 62 (53.45%) were women and 54 (46.55%) were men. The highest level of ferritin based on the age of the examined patients was 6 months to 1 year and then 1 to 3 years, 90% of children were normal in terms of heart diseases, 4.3% MILD TR and 2.6% MILD TR & MR and 2.6 percent were MOD TR + SEVER MR + RV, LV HYPERTROPHY. Ferritin in children and infants with covid disease was lower in females and the statistical analysis of the data showed that there is a significant relationship between ferritin and heart diseases in female covid patients as opposed to males in covid patients in infants and children. Ferritin was significantly higher in covid patients under 6 months who had heart diseases, but this relationship is negligible in other categories. Conclusion Serum ferritin level is a predictive factor for acquired cardiovascular disorders, the increase of ferritin level has a high correlation with the severity of heart diseases, so it has a high prognostic potential in children suffered from covid .