Phylogenomic analysis of African swine fever virus isolates from the Philippines

  1. Szarina Krisha K. Ko
  2. Rohani C. Navarro
  3. Ma Jowina H. Galarion
  4. Gabriela Ilona B. Janairo
  5. Adrian B. Abarientos
  6. Rachel R. Azul
  7. Cristina F. Legaspi
  8. Jennifer L. Maravilla
  9. Brian E. Schwem
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Abstract

African swine fever (ASF) is a re-emerging viral disease of swine, causing highly contagious hemorrhagic infection and devastating mortality in domestic pigs. It was first reported in the Philippines in July 2019 and outbreaks have since spread nationwide, reportedly reducing 30% of the local swine population. The present study aims to analyze the phylogenomic characteristics of two ASF virus isolates collected from outbreaks in the Philippines in May and June of 2020. Downstream analysis of short read metagenomic Illumina sequencing data generated two near full-length genome sequences of ASF viruses of genotype 2, serogroup 8, CVR 1, and IGR II. The current study identified 33 genetic variations within the Philippine isolates relative to ASFV Georgia 2007/1.

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  1. Version published to 10.21203/rs.3.rs-4379807/v1 on Research Square