An effcient strategy for halogenation addition of olefins catalyzed by Polyoxometalate-based Iron Catalyst

The halogenation of alkenes is a crucial pathway in forming C-X bonds, with significant impact in organic synthesis and pharmaceuticals. However, traditional methodologies present potential hazards to both the environment and human health, making the quest for green and efficient halogenation methods paramount. In this study, we introduce a novel iron catalyst based on a polyoxomolybdate, (NH ₄ ) ₃ [FeMo ₆ O ₁₈ (OH) ₆ ], simplified as Fe(III)Mo ₆ . Employing this catalyst, a plethora of styrene derivatives and alcohols were efficiently and successfully converted to the corresponding halogenated products. Also, our catalysts showed excellent performance towards to the reaction with various substrates. Moreover, it demonstrates high stability and activity in cycle test. In addition, we also described the reaction mechanism based on the control experiment. The catalyst exhibits non-toxic, green, and environmentally friendly characteristics that provide future industrialization potential.