Using D.SAP, an apple-based formulation for treatment of human papilloma virus, a case report

The Human papilloma virus (HPV) with almost 1% of prevalence in sexually active adults has more than thirty-five (HPV) types, that can infect the genital tract in women and cause a visible genital HPV infection and genital warts that reveal on the cervix, vagina, urethra, anus, and surrounding areas are mostly caused by HPV genotypes 6, 11 and 18. Moreover, the oncogenic HPV types including 16,18,31,33 and 35 are detected in most of the genital warts and are significantly associated with intraepithelial neoplasia of vulval (VIN), cervical (CIN), and anal (AIN). About fifty percent of the infected group have a subclinical or latent infection. Some of the HPV types can cause cervical, vaginal, and vulvar cancers. The most common treatment methods for removal of the HPV-induced vaginal warts are including cryotherapy, electrocautery, laser therapy, surgery, or trichloroacetic acid. In the present case report the treatment of a 41 years old woman with HPV infection and HPV-induced vaginal warts using an Iranian specially formulated apple-based sap called Dezhakam sap (D.SAP) has been presented. Results showed the disappearance of warts on the vaginal area, and replacement with normal tissue after three months of treatment. D.SAP is an antioxidant and probiotic-rich compound that could help the immune system fight against HPV infections and may present as a potential complementary therapy for HPV-induced warts.