Simulation of skin cancer by fixed and mobile laser with a complete set of equations

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Abstract

Recently, the prediction of cancer treatment via computer tools has been interesting to researchers. photothermal therapy is the most important non-invasive treatment for cancer therapy. during this method, the overheating problems, and damage to the healthy tissue are very important factors for complete and efficient treatment. here, for overcoming to this issue, we proposed the mobile laser for uniform irradiation on the tumor region embedded with gold nanoparticles. For considering the mobile laser, we have used a two-energy equation and investigated the heat field to understand treatment behavior. By increasing the laser intensity, the temperature of the tumor is increased in two cases of mobile and fixed laser, but the healthy tissue was damaged by the fixed laser. For temperature control, the volume fraction of gold nanoparticles can adjust the thermal absorbed by the tumor. the high values of volume fraction cause more energy absorption and the low values cause the greater depth of light propagation, which leads to a uniform distribution of the heat. Finally, the mobile laser was very efficient for thermal therapy without damaging the healthy tissues.

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