Co-infection of Fowl Cholera with bacterial and viral infection in poultry flocks

This study explores the co-infection dynamics of Pasteurella multocida ( P.multocida ) in poultry, focusing on Avian Leukosis Virus (ALV), Mycoplasma gallisepticum (MG), and Chicken Anemia Virus (CAV). Co-infections pose significant challenges to poultry health, leading to increased morbidity and mortality rates. The combined impact of co-infection exacerbates respiratory issues, weakens the immune system, and leads to intricate clinical manifestations. Samples from poultry flocks in Telangana and Haryana states of India, suspected for fowl cholera, were collected during 2019–2021. The study confirms co-infections using conventional PCR techniques targeting specific gene regions. Clinical symptoms exhibited by infected birds are described for each pathogen. The epidemiology of co-infections is discussed, and the importance of understanding these dynamics for effective control and prevention strategies is emphasized. Results reveal consistent co-infections over the study period, highlighting the need for further investigations into associations with parasites, bacteria, fungi, or viruses. The study underscores the importance of comprehensive biosecurity measures, vaccination programs, and early detection for managing poultry co-infections and ensuring sustainable production.