Green and Facile Synthesis of Silver–Dextran Nanocomposite Using Quince (Cydonia oblonga) Peel Extract: A Value-Added Agro-Waste Approach for Antibacterial Application

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Abstract

In this study, a green, simple, and scalable approach was developed for the synthesis of a silver–dextran nanocomposite (Ag–Dex NC) using quince ( Cydonia oblonga ) peel extract, an abundant agro-waste, was successfully developed. Secondary metabolites in the peel acted as natural reducing agents, facilitating the reduction of Ag⁺ ions to metallic Ag⁰ and enabling the formation of Ag nanoparticles (Ag NPs). Dex functioned as a polymeric capping and steric stabilizing matrix, embedding the Ag NPs and preventing aggregation, thus enhancing colloidal stability. NC formation was visually indicated by a color change. Structural and morphological characterization of the Ag–Dex NC was performed using ultraviolet–visible spectroscopy (UV–Vis), zeta potential analysis, field emission scanning electron microscopy (FE-SEM), Fourier-transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), and energy-dispersive X-ray spectroscopy (EDX). The results confirmed the formation of predominantly spherical, uniformly distributed AgNPs ranging from approximately 35 to 66 nm, with an average size of 52.57 ± 9.19 nm, embedded within the Dex matrix. The negative zeta potential indicated good colloidal stability. The Ag–Dex NC exhibited concentration-dependent antibacterial activity against Staphylococcus aureus ( S. aureus ) and Escherichia coli ( E. coli ), with stronger effects against S. aureus . These results highlight the synergistic role of Dex and peel metabolites in enhancing NP stability and bioactivity. This method offers a sustainable, low-cost, and environmentally friendly approach for producing Ag–Dex NC with notable antibacterial activity. The findings suggest potential future applications in antimicrobial coatings and packaging, subject to further studies and evaluation. Moreover, this study highlights the industrial potential of valorizing agricultural waste.

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