Phage Therapy: Leveraging Machine Learning and Big Data techniques to Unveil the Evolution, Innovations, and Global Landscape in the Fight Against Antibiotic Resistance

Phage therapy patent analysis, spanning from 1955 to 2023, reveals a substantial growth in the field, particularly since the early 2000s, with a peak in patent filings in 2021. The study identified key thematic areas, with “Compositions for Bacterial Infection Treatment” being the most prominent among the ten identified topics. Geographically, Asia, especially China, emerged as a leader in patent production, although U.S. patents showed greater citation impact, indicating a significant influence on global research. The analysis also highlighted diverse sectoral contributions with commercial and academic entities actively involved, and the importance of collaborative dynamics in driving innovation. This underscores a dynamic, evolving landscape in phage therapy, marked by regional disparities and a shift in research focus towards broad-spectrum medical applications and treatments for bacterial infections.