Prader-Willi Syndrome and Bariatric Surgery: A Case of Successful Laparoscopic Sleeve Gastrectomy in a Super-Obese Patient

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Abstract

Background: Prader-Willi syndrome is a genomic imprinting error characterized by short stature, multiple endocrine disorders, dysmorphic features, scoliosis, osteoporosis, mental retardation, behavioral and psychiatric disorders, making its management a multidisciplinary challenge. Case presentation: This case report presents a 27-year-old woman with Prader-Willi syndrome (PWS), a body mass index (BMI) of 79.8, obstructive sleep apnea (OSA) and prediabetes treated with laparoscopic sleeve gastrectomy (LSG), the patient exhibited a marked improvement in (BMI) from 79.8 to 62 within 6 months post-surgery (22% reduction) with no significant complications. Conclusion: This case highlights the potential efficacy of LSG as a surgical intervention for obesity in individuals with PWS.

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