Current Real-Life Survival After Segmentectomy for Lung Cancer

Introduction: Segmentectomy for non–small cell lung cancer (NSCLC) is increasingly performed for small-sized lesions. However, prognostic factors associated with poor out-comes after this lung-sparing oncologic surgery remain unclear. Methods: We conducted a single-center retrospective study including 100 patients who underwent segmentectomy in real-life practice. Results: Univariate analyses identified compromise segmentectomy (HR 3.52; p = 0.005), complex segmentectomy (HR 2.56; p = 0.02), resection of a lesion with SUVmax > 6 (HR 2.86; p = 0.017), and thoracotomy approach (HR 2.62; p = 0.02) as risk factors for mortality. Regarding recurrence, thoracotomy (HR 2,77; p= 0,04) was a poor prognostic factor. Conclusion: We have identified risk factors for mortality and recurrence after segmentectomy and highlighted the need for improved assessment of the manage-ment of patients candidates for compromise segmentectomies.