Progress in Clinical Magnetocardiography: The Contactless Breakthrough for Non-Invasive Clinical Detection of Cardiac Ischemia Now Needs Worldwide Standardization

Magnetocardiography has reached its clinical breakthrough, at least as a contactless, highly sensitive method to diagnose or exclude an ischemic cardiomyopathy, with or without coronary obstruction, in patients with chest pain of uncertain origin and still normal troponin and ECG patterns. This diagnostic advantage has already been recognized with regulatory approvals. However, despite its intrinsic advantages, including unrivalled non-invasive inverse estimation of cardiac currents and a strong potential for 3D- and 4D multimodal integration with other imaging modalities, its clinical adoption remains limited by the absence of internationally shared standards. This perspective review aims to highlight the point of view of the clinical end-user and propose the establishment of an interdisciplinary expert commission for the standardization and interpretation, now essential to define consensus-based recommendations for MCG clinical use.