Unified Approaches in Modern Drug Delivery Covering Lipid Based Nanocarriers Controlled Release Mechanisms and Innovative Tablet Technologies

The drug delivery system of today is made up of heap of innovations like lipid-based nanocarriers, controlled-release technologies, and rapidly developing oral dosage forms. The present article is the first to provide an exhaustive coverage of the latest methods along with their benefits that include greater therapeutic effectiveness, better patient compliance, and flexibility in formulation. One of these methods is the use of lipid nanoparticles: liposomes, solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), and other vesicular systems which are responsible for the better solubility, permeability and stability of difficult bioactive molecules. Their compatibility with oral dosage forms has resulted in improving gastrointestinal absorption, targeted delivery, and sustained exposure.The controlled-release systems have come a long way too, offering the most sophisticated modulation of drug release through diffusion, erosion, osmotic, and swelling mechanisms. The systems yield predictable pharmacokinetic profiles and reduce dosing frequency, while oral controlled-release strategies' innovations open the door for an application in various therapeutic categories. In the meantime, oral dosage technologies such as fast-dissolving tablets, effervescent systems, QbD-based solid dosage forms, and 3D-printed tablets are signs of the growing patient-centric and customizable therapeutic design themes.The amalgamation of nanocarriers with state-of-the-art oral and controlled-release systems leads to the formation of synergistic platforms that are capable of delivering drugs with very high bioavailability and targeted delivery. Future directions indicate the pathways of transporter-mediated absorption, AI-assisted formulation optimization, and new capsule-based inventions as revolutionary players of drug delivery in the next generation. The advances mentioned above form a united pattern for future pharmaceutical development that is based on creative ideas, accuracy, and improved efficiency in therapy.