Importance of Rajan Risk Score in Predicting Mortality in Patients with Heart Failure Irrespective of Ejection Fraction. mR-hf Score's Prognostic Value in HF

Background and Objectives: To date, the role of the modified Rajan’s heart failure (mR-hf) risk score has been studied in patients with heart failure with reduced (HFrEF) and mid-range ejection fraction (EF). However, it has not been investigated in subjects with preserved EF (HFpEF). We aimed to examine the predictive value of the mR-hf risk score for mortality in both HFrEF and HFpEF. Methods: A total of 220 patients with HFrEF and HFpEF were included in this retrospective study. The study sample was divided into two groups according to mortality. Findings were compared between the groups. Results: The Non-survived group included 27 subjects, while the Survived group comprised 193 patients. The mR-hf risk score was significantly lower in the Non-survived group than the Survived group (p<0.001). According to the multivariate analysis, the mR-hf risk score and New York Heart Association (NYHA) classification were independently associated with all-cause mortality (OR: 0.938, 95% CI: 0.905-0.972; p<0.001 and OR: 2.278, 95% CI: 1.161-4.468; p=0.017, respectively). Furthermore, the mR-hf risk score predicted mortality in both HFrEF and HFpEF (p values, <0.015 and <0.004, respectively). Conclusion: The mR-hf risk score could be a simple tool for predicting mortality in patients with HF, irrespective of EF.