Study of Biological Safety of Camel Milk After Treatment by Albendazole and Ivermectin

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Abstract

The problem of medicine residues as Albendazole and Ivermectin in milk is a current question in food safety. No data being available for camel, the present study aimed to assess the risk of antiparasitic residues in camel milk after injection at curative dose. For the experiment, 10 camels shared in two groups where used for Albendazole and Ivermectin respectively and milk samples were taken every day the first 4 days, then approximately every 2 weeks for 6 months. In addition, blood samples were taken in Ivermectin group. The samples were analysed by HPLC. One average for Albendazole, the maximum concentration appeared on day 2 (52 ± 65.2 µg/mL) and day 48 (50 ± 63.1 µg/mL). and after 210 days, the residues remained at around 11 µg/mL. The kinetic in blood showed a slight shift with that of milk during the first days of the experiment, but there was no significant difference between them. For Ivermectin, one peak only appeared at date 101 (0,96 ± 1,19 µg/mL) and after 172 days, the mean concentration was still 0.12 µg/mL. The persistence of the residues long time after injection lead to consider that specific guidelines should be proposed for camel.

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