Efficiency of Recurrent Genomic Selection in Panmictic Populations

Simulation-based studies provide knowledge that cannot be offered by the analysis of em-pirical data. The objective of this simulation-based study was to assess the efficiency of recurrent genomic selection in panmictic population under additive-dominance and ad-ditive-dominance with epistasis models. We assumed two broiler chicken populations with contrasting linkage disequilibrium (LD) levels, 38500 SNPs, and 1000 genes control-ling feed conversion ratio. We applied recurrent genomic selection over seven cycles. The genomic selection efficacy, expressed as realized total genetic gain, is proportional to the LD level and genotypic variance. Genomic selection requires model updating to achieve a higher efficacy. The training set size required by genomic selection can be as low as 10%/generation. Under this low-cost scenario, the genomic selection efficacy was slightly lower than the maximum efficacy. There is no difference between genetic evaluation methods regarding the decrease in the genotypic variance due to selection. In general, ad-ditive value prediction accuracies and realized genetic gains were highly correlated. The accumulated inbreeding level was not high due to avoidance of sib cross. The genomic inbreeding coefficient over generations was close to zero. Except for dominant epistasis, the efficacy of genomic selection was 4.1 to 46.2% lower than the efficacy under no epistasis.