Allosteric Control Overcomes Steric Limitations for Neutralizing Antibodies Targeting Conserved Binding Epitopes of the SARS-CoV-2 Spike Protein: Exploring the Intersection of Binding, Allostery and Immune Escape with Multimodal Computational Approach
Listed in
This article is not in any list yet, why not save it to one of your lists.Abstract
Keywords: SARS-CoV-2 spike protein; Omicron variants; antibody binding; immune escape; molecular dynamics; protein stability; mutational scanning; binding energetics; ; evolutionary mechanisms