Cholecystectomy in the Context of Cirrhosis, Sclero-Atrophic Cholecystitis and Gangrenous Cholecystitis: A Literature Review

The gallbladder pathology is mainly represented by cholelithiasis, 6% of the world’s population being diagnosed with this medical disorder, according to World Health Organization. Cholecystectomy, one of the most commonly performed surgical procedures, continues to raise some challenges, despite the advancements in surgical techniques, especially in those patients presenting some particularities, such as cirrhotic patients or those with sclero-atrophic or acute gangrenous cholecystitis. This review, including an evaluation of the literature from the last 20 years, aims to explore the pathophysiological mechanisms and surgical approaches for these high-risk conditions. Emphasis is placed on tailoring management strategies in order to reduce complications and improve outcomes, offering insights for optimizing care in difficult cholecystectomies.