Comparative Efficacy of Dorsal Root Ganglion Versus Spinal Cord Stimulation in the Management of Complex Regional Pain Syndrome and Failed Back Surgery Syndrome: A Narrative Review

Background: Complex Regional Pain Syndrome (CRPS) and Failed Back Surgery Syndrome (FBSS) are challenging neuropathic pain conditions often refractory to conservative treatment. Neuromodulation offers a promising solution, particularly with spinal cord stimulation (SCS) and dorsal root ganglion stimulation (DRG-S). Objective: This review compares DRG-S and SCS in CRPS and FBSS to evaluate their relative efficacy, safety, and clinical utility. Methods: A narrative literature review was conducted using peer-reviewed sources focusing on the use of DRG-S and SCS in CRPS and FBSS populations. Results: DRG-S offers enhanced targeting of focal pain areas in CRPS, while SCS provides broader coverage useful in FBSS. DRG-S demonstrates superior outcomes in CRPS regarding pain relief and functional improvement. Lead migration, a common complication in both, is reportedly lower in DRG-S. Conclusion: DRG-S is particularly effective in CRPS due to precise anatomic targeting, while SCS remains valuable in FBSS. Further randomized studies are needed to confirm long-term comparative efficacy.