Relationship Between Maternal High Risk Human Papillomavirus Infection and Pregnancy Outcomes

Aim: The aim of this study was to evaluate the relationship between maternal HR-HPV (high risk) infection and pregnancy outcomes. Materials and Methods: Among 5840 women who gave birth between 2016-2023, a total of 1042 patients, 146 (14%) HR-HPV (+) and 896 (86%) HR-HPV (-), who had cervical cancer screening test results within 1 year and met the eligibility criteria, were retrospectively evaluated. Age, parity, Apgar score, smoking status, history of premature rupture of membranes (PROM) were retrospectively reviewed from medical records. Results: The mean BMI of HR-HPV (+) patients was determined to be 26.2 kg/m2, which was significantly higher than the (-) group (p< 0.001). The smoking rate of HR-HPV (+) patients was found to be significantly higher than the (-) group (p=0.04). No significant difference was found between HR-HPV (+) and (-) patients in terms of PROM rates and preterm delivery rates (p=0.2, p=0.9 respectively). No significant difference was found between HR-HPV (+) and (-) patients in terms of preeclampsia rates and GDM rates (p=0.4, p=0.6 respectively). Conclusion: We could not clearly demonstrate a relationship between HR-HPV infection and perinatal and neonatal outcomes. Further studies are needed to evaluate the effects of HR-HPV infection on pregnancy outcomes.