A Dietary Intervention with a Synbiotic Beverage on Women with Type 2 Diabetes, Overweight and Obesity<i></i>

Introduction: Non committable chronic diseases such as overweight and obesity are considered in high risk for type 2 diabetes. Around the world, there are 536.6 million people with diabetes. Mexico represents a high prevalence of these diseases. Objective: Evaluate the effect of a synbiotic beverage and a 12-week dietary intervention on body composition and biochemical parameters in women with T2D, overweight or obesity, to obtain an additional strategy as treatment. Methods: A double-blinded, randomized and experimental in a 12 week dietary intervention with a synbiotic fermented beverage with a n=51 women divided in 4 groups: G1 followed a moderate calorie-restricted diet, G2 did the same moderate calorie-restricted diet and a synbiotic, G3 took only the synbiotic and G4 consumed a placebo beverage. Results: The total mean of ages of the 4 groups was 42.90 &plusmn; 10.6. The significant changes were in BMI (P&lt;0.001), fat mass (P&lt;0.001), HOMA-index (P&lt;0.001) and serum insulin serum (P&lt;0.001), after the 12 week dietary intervention, proving the effect of the synbiotic. Conclusion: Significant decreases in different body composition and biochemical profiles were proved showing the benefits of the beverage. Further research is needed in gut microbiota profile in this kind of participants.