Pilot Randomized Controlled Trial of iCanWork: A Theory-Guided Return to Work Intervention for Cancer Survivors

Background: Return to work (RTW) after cancer can be a significant challenge with individuals when it comes to return to work (RTW), including physical, psychological, and workplace-related barriers. iCanWork, a multidisciplinary intervention integrating vocational rehabilitation (VR) and occupational therapy (OT), aims to address these challenges and promote sustainable RTW. Methods: This pilot randomized controlled trial evaluated the feasibility, acceptability, and preliminary efficacy of iCanWork among 23 individuals touched by cancer (ITBC) randomized to the intervention or control group. Feasibility was assessed by recruitment, retention, and adherence benchmarks. Acceptability was evaluated using participant satisfaction surveys. Preliminary efficacy was measured through RTW status, Work Ability Index (WAI) scores, and health-related quality of life (QoL) outcomes. Results: Feasibility benchmarks were achieved (92% recruitment, 83% retention). Participants found the intervention highly satisfactory for its tailored support. The iCanWork group demonstrated modest improvements in WAI scores (mean change: +2.54) and QoL domains, including Social Roles, while the control group exhibited declines. However, no significant differences in RTW rates or WAI scores were observed between groups, highlighting the need for enhanced and prolonged interventions. Conclusions: he iCanWork intervention is feasible and acceptable, showing potential to address critical barriers to RTW for cancer survivors. Larger trials are warranted to confirm efficacy and optimize intervention strategies for sustainable employment outcomes.