Appropriate Antithrombotic Management for Older Adults Living with Dementia

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Abstract

Antithrombotic medication is recommended for individuals who have a history of atrial fibrillation, venous thromboembolism, acute coronary events, or post-percutaneous coronary intervention. The purpose of this study was to describe the use of antithrombotics among older adults living with dementia at hospital admission and 1-month follow-up, treatments prescribed, and associated complications. The sample included 404 hospitalized older adults living with dementia, the majority of whom were White females, mean age in years of 82 (SD = 8). On admission, 69% of the patients were on at least one antithrombotic medication, and at 1-month post-discharge, this decreased to 64%. At 1-month post-discharge, the percentage of individuals on two or more antithrombotics decreased from admission at 34% to 14%. On admission, 11 (4%) of patients were admitted with adverse events from antithrombotics, and at 1-month post-discharge 5 (2%), patients were readmitted due to adverse events from antithrombotics. Given the risks and benefits of antithrombotic use among older adults living with dementia, a shared decision-making approach with patients and caregivers is recommended. This approach is the best way to help patients achieve their individual goals of care.

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