Effect Of Copper And Magnesium Oxide Nanocomposite In Mcf-7 Cell Line

Background: Nanoparticle particle and nanomaterials are increasingly being explored for their potential application in medicine. One of the most promising areas of application is drug delivery, where nanoparticle can be used as carriers to deliver drugs to specific cells or tissues in the body. The cancer is the major cause of morbidity and mortality and still today there isn’t any promising therapeutics for treating cancer. • Methods: The nanocomposite of copper and magnesium oxide nanoparticle is synthesized from copper sulphate and magnesium sulphate as starting material. Sodium hydroxide act as a reducing and capping agent in the nanoparticle synthesis. After synthesis, the nanoparticles were characterized by UV-spectrophotometer, FT-IR, SEM, DLS and zeta potential. • Results: The crystalline morphology and size of the nanoparticles were determined by DLS and SEM analysis. Furthermore, anti-microbial activities were evaluated. The cytotoxicity of the different concertation of the nanocomposite of copper and magnesium oxide nanoparticle is tested against MCF-7 cell line. Conclusion: It is concluded that the nanocomposite was synthesized chemically by the sol-gel method. After all the characterization, the nanocomposite was tested for antimicrobial activity and cytotoxicity. The cytotoxicity study shows better cell cytotoxicity against MCF-7 cells. Further animal studies need to confirm the effectiveness of the nanocomposite.