Oral Health as a Determinant in Preventing Cellular Aging and Promoting Immune Sustainability
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Background: This study assessed the effects of ceramic dental implant placement on inflamma-tory responses, immune function, and cellular aging in a 53-year-old female patient. Objective: This study aimed to determine whether minimally invasive implant procedures combined with regenerative techniques can influence biological aging and systemic inflammation. Methods: A comprehensive treatment approach was used, including minimally invasive ceramic dental im-plant placement, platelet-rich fibrin (PRF) augmentation, and vitamin supplementation. Advanced imaging and biomarker analyses have evaluated implant osseointegration, inflammatory pro-files, immune responses, and telomere length as markers of cellular health and aging. Results: Successful implant osseointegration was observed along with a favorable inflammatory profile, as reflected by increased levels of the anti-inflammatory cytokine IL-10. An improvement in telo-mere length suggests potential benefits to cellular health. However, a slight increase in biological aging was observed, as indicated by the glycan profile. These findings underscore the complex interactions between oral health, systemic inflammation, and biological aging. Conclusions: This study provides new insights into the regenerative and anti-aging potential of dental treatments, indicating that ceramic dental implants combined with regenerative therapies may reduce im-munological stress and support healthy aging. Although reduced inflammation and improved oral function are evident, the long-term effects on cellular aging and longevity remain unclear. Further studies are needed to better understand the impact of these interventions on biological aging and overall health.