Hypertension in Patients Hospitalized with COVID-19 in Wuhan, China

  1. Yuan Zhang
  2. Tong Sha
  3. Feng Wu
  4. Hongbin Hu
  5. Zhongqing Chen
  6. Haijun Li
  7. Jiafa Han
  8. Wenhong Song
  9. Qiaobing Huang
  10. Zhenhua Zeng

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Abstract

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  1. Version published to 10.1536/ihj.20-323
  2. ScreenIT

    SciScore for 10.1101/2020.04.06.20054825: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Institutional Review Board StatementIRB: This study was approved by the National Health Commission of China and the Ethics Commission of Hankou Hospital (hkyy2020-005).
    Consent: The Ethics Commission of Hankou Hospital waived the requirement for obtaining informed consent.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.
    Sex as a biological variablenot detected.

    Table 2: Resources

    Software and Algorithms
    SentencesResources
    Statistical analysis: Statistical analysis was performed using SPSS software for Windows, version 20.0 IBM Corp.,
    SPSS
    suggested: (SPSS, RRID:SCR_002865)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:
    Our research has the following limitations: First, our survey only focused on Hankou Hospital in Wuhan, and the number of patients included was small; larger sample size and multi-center clinical data will be needed to support our conclusions in a future study. Second, our investigation included all clinically confirmed cases. Many patients were not tested because of the lack of nucleic acid test kits at the beginning of the outbreak. Further, there were some patients were suspected to have COVID-19 but were excluded from our study because they tested negative in the hospital; however, based on the exact epidemiological history, the patient’s signs and symptoms, and chest CT examination results, we trust the reliability of the COVID-19 diagnosis in these patients. Third, due to the urgent data collection, we had a shorter follow-up time for some patients. The shortest hospital stay for patients is only > 14 days. This may interfere with the final prognosis and lead to the failure to analyze survival times. Fourth, we did not analyze the comorbidities such as shock and ARDS, because our focus is to analyze the risk associated with hypertension to provide evidence for the issue of COVID-19 prevention and treatment guidelines. Perspectives: COVID-19 patients with coexisting hypertension were significantly older and were more likely to have underlying comorbidities, including chronic renal insufficiency, cardiovascular disease, diabetes mellitus, and cerebrovascular disease. Pati...

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  3. Version published to 10.1101/2020.04.06.20054825v1 on medRxiv