Development of a multivariate prediction model of intensive care unit transfer or death: A French prospective cohort study of hospitalized COVID-19 patients
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SciScore for 10.1101/2020.05.04.20090118: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IACUC: 12 We received local ethical committee approval, and our study is registered as (NCT04320017). Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Our study has several limitations. We present models, with both internal and external validation. Discrimination of the model and of the …
SciScore for 10.1101/2020.05.04.20090118: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Institutional Review Board Statement IACUC: 12 We received local ethical committee approval, and our study is registered as (NCT04320017). Randomization not detected. Blinding not detected. Power Analysis not detected. Sex as a biological variable not detected. Table 2: Resources
No key resources detected.
Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: We detected the following sentences addressing limitations in the study:Our study has several limitations. We present models, with both internal and external validation. Discrimination of the model and of the simplified score was consistent in the external cohort. Calibration assessment showed that the model and score slightly overestimated the risk of event in the external cohort, in patients with higher scores. The external sample was one of patients from a regional non-university hospital (Aulnay-sous-Bois, Île-de-France) which could explain differences on catchment area and patient recruitment. Further external validation on large prospective cohorts will be useful. To our knowledge, this is the first prospective European cohort of COVID-19 non-critical inpatients and one of the largest standardized studies describing short term patients outcome. We provided a very simple and easily accessible score to estimate the risk of ICU transfer or death by day 14. In the context of the pandemic, this tool can help the management of patient flow, and also clinical trial design and therapeutic management.
Results from TrialIdentifier: We found the following clinical trial numbers in your paper:
Identifier Status Title NCT04320017 Recruiting Joint Use of Electrocardiogram and Transthoracic Echocardiog… Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
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