Binding and neutralizing antibody responses to SARS-CoV-2 in very young children exceed those in adults
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SciScore for 10.1101/2021.12.20.21268034: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics Consent: Prior to study participation, all participants or their parents/guardians provided informed consent, and children aged 7 years and older also provided assent.
IRB: The study protocol was reviewed and approved by the Johns Hopkins Bloomberg School of Public Health Institutional Review Board (IRB).Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources Data were collected using Research Electronic Data Capture (REDCap). REDCapsuggested: (REDCap, RRID:SCR_003445)Statistical analysis: Analyses were performed using Graphpad Prism (San Diego, CA) and in R version . Graphpad …SciScore for 10.1101/2021.12.20.21268034: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics Consent: Prior to study participation, all participants or their parents/guardians provided informed consent, and children aged 7 years and older also provided assent.
IRB: The study protocol was reviewed and approved by the Johns Hopkins Bloomberg School of Public Health Institutional Review Board (IRB).Sex as a biological variable not detected. Randomization not detected. Blinding not detected. Power Analysis not detected. Table 2: Resources
Software and Algorithms Sentences Resources Data were collected using Research Electronic Data Capture (REDCap). REDCapsuggested: (REDCap, RRID:SCR_003445)Statistical analysis: Analyses were performed using Graphpad Prism (San Diego, CA) and in R version . Graphpad Prismsuggested: (GraphPad Prism, RRID:SCR_002798)1.0 (R Foundation for Statistical Computing) in RStudio version 1.4.1717 (RStudio, Inc). RStudiosuggested: (RStudio, RRID:SCR_000432)Figures were generated using Graphpad Prism and the Ggplot2 package. Ggplot2suggested: (ggplot2, RRID:SCR_014601)Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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