Expectation effects on repetition suppression in nociception

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Abstract

We show that repetition suppression (RS; the diminished neural activity upon repeated stimulus presentation) can be observed in the nociceptive domain: brief laser stimuli lead to RS in event-related potentials and gamma oscillations. Importantly, nociceptive RS is not modulated by repetition probability and thus expectations regarding the occurrence of a repetition. This indicates that nociceptive responses are less prone to top-down expectations under conditions of limited sensory uncertainty, as established via precise laser stimuli.

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