The Usefulness of Antigen Testing in Predicting Contagiousness in COVID-19
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Abstract
The importance of our results is the excellent agreement between the Standard Q COVID-19 antigen test and the viral culture, indicating that it is important as a marker of contagiousness. Due to its high positive predictive value in situations of a high prevalence of infection, positive results do not require confirmation with another test.
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SciScore for 10.1101/2021.10.16.21265067: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics Consent: We excluded pediatric patients and individuals who were unwilling to provide their written consent.
IRB: It was approved by the Ethics Committee of the Universidad de Antioquia (Act. 004, 02-04-2020).Sex as a biological variable not detected. Randomization not detected. Blinding The antigen tests were evaluated independently by two laboratory technicians blinded to the RT-PCR and viral culture results. Power Analysis not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources This solution was inoculated into 1 × 105 Vero E6 cells monolayers in 12-well plates and incubated for 90 min at 37° C with 5% CO2. Vero E6suggested: None… SciScore for 10.1101/2021.10.16.21265067: (What is this?)
Please note, not all rigor criteria are appropriate for all manuscripts.
Table 1: Rigor
Ethics Consent: We excluded pediatric patients and individuals who were unwilling to provide their written consent.
IRB: It was approved by the Ethics Committee of the Universidad de Antioquia (Act. 004, 02-04-2020).Sex as a biological variable not detected. Randomization not detected. Blinding The antigen tests were evaluated independently by two laboratory technicians blinded to the RT-PCR and viral culture results. Power Analysis not detected. Cell Line Authentication not detected. Table 2: Resources
Experimental Models: Cell Lines Sentences Resources This solution was inoculated into 1 × 105 Vero E6 cells monolayers in 12-well plates and incubated for 90 min at 37° C with 5% CO2. Vero E6suggested: NoneSoftware and Algorithms Sentences Resources Statistical analysis: The Standard Q COVID-19 Ag test was evaluated using the sensitivity, specificity, predictive value, and likelihood ratio calculated using GrapdPad Prism (version 9, California, USA), R v4.1.0, and the Integrated Development Environment Rstudio. GrapdPad Prismsuggested: NoneResults from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).
Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.Results from TrialIdentifier: No clinical trial numbers were referenced.
Results from Barzooka: We did not find any issues relating to the usage of bar graphs.
Results from JetFighter: We did not find any issues relating to colormaps.
Results from rtransparent:- Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
- Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
- No protocol registration statement was detected.
Results from scite Reference Check: We found no unreliable references.
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