The role of endotheliitis in COVID‐19: Real‐world experience of 11 190 patients and literature review for a pathophysiological map to clinical categorisation

  1. Adem Dirican
  2. Selin Ildir
  3. Tugce Uzar
  4. Irem Karaman
  5. Sevket Ozkaya

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Abstract

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  1. Version published to 10.1111/ijcp.14843
  2. Version published to 10.1101/2021.07.05.21259790v2 on medRxiv
  3. ScreenIT

    SciScore for 10.1101/2021.07.05.21259790: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    Ethicsnot detected.
    Sex as a biological variableThe mean age was 59.2 ±17.3 years and male to female ratio was 5507/5683.
    Randomizationnot detected.
    Blindingnot detected.
    Power Analysisnot detected.

    Table 2: Resources

    Antibodies
    SentencesResources
    Patients who were suspected to be infected by SARS-CoV-2 were confirmed with clinic, laboratory (positive reverse-transcriptase–polymerase-chain-reaction assay of nasopharyngeal swabs or serological IgM/IgG rapid antibody test against SARS-CoV-2) and radiologic (consistent HRCT findings) results and included in the study.
    SARS-CoV-2
    suggested: None
    Software and Algorithms
    SentencesResources
    Evaluation of Patients with Laboratuary, Course and Prognosis: Our classification of treatment was primarily based on the clinical and radiological findings.
    Prognosis
    suggested: None

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  4. Version published to 10.1101/2021.07.05.21259790v1 on medRxiv