Use of surgical antimicrobial prophylaxis and magnitude of surgical site infections among surgical patients at Hiwot Fana Comprehensive Specialized Hospital, Harar, Ethiopia
Discuss this preprint
Start a discussion What are Sciety discussions?Listed in
This article is not in any list yet, why not save it to one of your lists.Abstract
Background
Surgical site infections (SSIs) remain a common complication after surgery, particularly in low-resource settings. This study assessed the use of surgical antimicrobial prophylaxis (SAP) and the magnitude of SSI among Surgical patients at Hiwot Fana Comprehensive Specialised Hospital, Harar, Ethiopia.
Methods
A hospital-based retrospective chart review was conducted among 297 randomly selected patient records from November 2022 to October 2023. Data were analyzed using descriptive statistics and logistic regression to identify factors associated wth SSI.
Results
SAP was administered to 96 % of patients, predominantly ceftriaxone (72%). The overall SSI rate was 10.9 % (95% CI: 7.1-14.1). Factors significantly associated with SSI included comorbidity, previous surgery, ASA score ≥2, emergency procedures, contaminated/dirty wounds, and lack of prophylaxis.
Conclusion
Despite high SAP utilization, SSI prevalence remains moderate. Strengthening adherence to surgical antibiotic prophylaxis guidelines and optimizing timing and antibiotic choice are recommended to further reduce SSIs.
