Atmospheric pattern correlates of human brain structure

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Abstract

Climate change increasingly impacts human health, yet its neurobiological effects remain poorly understood. Analysing structural neuroimaging data of 30,831 UK participants (4,294 with follow-up assessments), we show that ambient weather conditions (warm, sunny, low precipitation and wind speed) associate with brain structure variations that exceed contributions from Alzheimer’s disease genetic risk scores and self-reported mental health. These findings establish atmospheroc patterns as measurable environmental correlates of brain structure and reveal new pathways for understanding climate-brain interactions.

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