Lineage H Rift Valley Fever Virus Drives Deadly 2025 Outbreak in Northern Senegal.

  1. Moussa Moise DIAGNE
  2. Gamou FALL
  3. Abiboulaye Sall
  4. Bocar Sow
  5. Ndeye Awa Ndiaye
  6. Alioune Gaye
  7. Mamadou Sarr Ndao
  8. Aboubacry Gaye
  9. El Hadji Ndiaye
  10. Seynabou Mbaye Ba Souna Diop
  11. Safietou Sankhe
  12. Mouhamed Kane
  13. Seynabou Ndiaye
  14. Ousmane Faye
  15. Yoro Sall
  16. Mamadou Aliou Barry
  17. Ibou Gueye
  18. Marie Henriette Dior Ndione
  19. Boly Diop
  20. Ousmane Cisse
  21. Joseph R A Fitchett
  22. Ibrahima Dia
  23. Cheikh Loucoubar
  24. Ndongo Dia
  25. Mawlouth Diallo
  26. Boubacar Diallo
  27. Ibrahima Soce Fall
  28. Mamadou Ndiaye
  29. Diawo Diallo
  30. Abdourahmane Sow
  31. Oumar Faye
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Abstract

In late September 2025, a deadly Rift Valley fever outbreak in northern Senegal caused 44 cases and 8 deaths. Sequencing confirmed lineage H persistence with three novel polymerase mutations suggesting adaptation. Ongoing concurrent One Health investigations target vectors, livestock, and human exposure to identify risk factors and strengthen control.

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  1. Version published to 10.1101/2025.10.08.25337605 on medRxiv