Venezuelan Equine Encephalitis Virus, Amazonas, Brazil, 2025

  1. Franklin Simões de Santana Filho
  2. Marcelo Ferreira dos Santos
  3. Victor Costa de Souza
  4. Valdinete Alves do Nascimento
  5. Maria do Perpétuo Socorro Lopes dos Santos
  6. Gian Pierre Hernandez Medina
  7. Klaus Estivens Lima Salazar
  8. Jhamylee Evellyn Sanchez Mendez
  9. Elizabeth Andreia da Silva Brito Fajardo
  10. Luis Castelo Branco de Oliveira
  11. David Siqueira da Costa
  12. Tyziane Machella Oliveira Torres
  13. Ana Cláudia Magalhães Salvador
  14. Syssi Helen Albuquerque do Nascimento
  15. Bruna Oliveira da Silva
  16. Karina Lopes Oliveira
  17. Herton Augusto Pinheiro Dantas
  18. Matilde Mejía
  19. Fernanda Nascimento
  20. Dejanane Silva
  21. Maria Julia Pessoa Brandão
  22. Ana Beatriz Vieira Muniz
  23. Tatiana Amaral Pires de Almeida
  24. Marco Aurélio Almeida de Oliveira
  25. Luciana Mara Fé Gonçalves
  26. Tatyana Costa Amorim Ramos
  27. Flor Ernestina Martinez-Espinosa
  28. André Reynaldo Santos Périssé
  29. Deusilene Souza Vieira Dall’Acqua
  30. Ana Maria Bispo de Filippis
  31. Gonzalo Bello
  32. Martha Cecília Suárez-Mutis
  33. Felipe Gomes Naveca
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Abstract

We report the first detection of Venezuelan Equine Encephalitis Virus (VEEV) in residents of Tabatinga, Amazonas, Brazil, a tri-border region with Colombia and Peru. Brazilian and Peruvian sequences clustered together, suggesting potential cross-border transmission. Our findings identify VEEV as an underrecognized etiology of acute febrile illness in the Brazilian Amazon.

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  1. Version published to 10.1101/2025.08.19.25333804 on medRxiv