Pervasive Intestinal Carriage with Multiple Species of Extended Spectrum Cephalosporin-Resistant Enterobacterales in Children Admitted for Severe Acute Malnutrition at a Tertiary Hospital in Malawi

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Abstract

Using culture-based screening of stool specimens, 80.3% of 188 children hospitalized for severe acute malnutrition in Malawi carried extended spectrum cephalosporin resistant Enterobacterales (ESCR-E) at admission. 38.3% of children were colonized with multiple ESCR-E species. Over half of the colonized children did not have recent antibiotic exposure or prior hospitalization.

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