CRITICAL ROLE OF ADULT-BORN DENTATE GRANULE NEURONS IN PATTERN COMPLETION’
Listed in
This article is not in any list yet, why not save it to one of your lists.Abstract
The dentate gyrus contains neurons generated during development and adulthood, yet their distinct roles remain unclear. Using a transgenic mouse model, we show that adult-born neurons contribute to pattern completion, essential for episodic memory. This has implications for aging, PTSD, and addiction, where excessive pattern completion leads to maladaptive memories. Targeting ABNs could offer new therapeutic strategies to regulate memory processes and improve mental health.
