Nonendoscopic Detection of Barrett's Esophagus on Patients Without Gastroesophageal Reflux Disease Symptoms
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Upper endoscopy (EGD) is generally recommended in those with chronic gastroesophageal reflux disease (GERD). To evaluate nonendoscopic screening in those without GERD symptoms.
METHODS:
EsoCheck/Esoguard (LucidDx) was performed in recruited patients without chronic GERD who had ≥3 other BE risk factors.
RESULTS:
The EsoGuard assay was positive in 34 of 120 patients. BE was identified in 9 of 27 who had follow-up EGD, positive predictive value = 33% (17%–54%). EGD performed in 22 of 86 subjects with negative assays found no BE, negative predictive value = 100% (85%–100%).
DISCUSSION:
Nonendoscopic BE detection is effective in patients without chronic GERD.
