Yellow fever virus resurgence in São Paulo State, Brazil, 2024-2025

  1. Mariana Sequetin Cunha
  2. Juliana Mariotti Guerra
  3. Márcio Junio Lima Siconelli
  4. Benedito Antonio Lopes da Fonseca
  5. Jessica Caroline de Almeida Dias
  6. Gisele Dias de Freitas
  7. Ester Sabino
  8. Erika R. Manulli
  9. Geovana M. Pereira
  10. Ian N. Valença
  11. Patrícia Sayuri Silvestre Matsumoto
  12. Nuno R. Faria
  13. Natália Coelho Couto de Azevedo Fernandes
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Abstract

Yellow fever virus (YFV) was detected in two distinct geographic locations in São Paulo State, Brazil, between September 2024 and February 2025. Phylogenetic analysis of six new genomes revealed a re-introduction in 2022 from Midwest Brazil followed by persistence in São Paulo state. Continued surveillance in neotropical primates is required to prevent cases in humans.

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  1. Version published to 10.1101/2025.03.14.25323956v1 on medRxiv