Unifying DNA methylation-based in silico cell-type deconvolution with deconvMe
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Summary
Cell-type deconvolution is widely applied to gene expression and DNA methylation data, but access to methods for the latter remains limited. We introduce deconvMe , a new R package that simplifies access to DNA methylation-based deconvolution methods predominantly for blood data, and we additionally compare their estimates to those from gene expression and experimental ground truth data using a unique matched blood dataset.
