Co-occurrence of Seizures and Gastrointestinal Symptoms in Children with ASD
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The goal of this cluster analysis of comorbidities in children with Autism Spectrum Disorder (ASD) was to find potential co-occurrence between health symptoms that would not otherwise be investigated. We analyzed parent-reported data from 130,985 users of a free language-learning application. The initial cohort was stratified by ASD severity and age group to explore patterns within these subpopulations. Across these cohorts and subgroups, we observed a consistent co-occurrence of gastrointestinal symptoms, such as diarrhea and constipation, with seizures and lethargy. These results suggest that a common underlying mechanism may be driving both gastrointestinal disturbances and seizure activity in children with ASD.
