WITHDRAWN: Asengeprast, a Novel G-Protein Coupled Receptor 68 Antagonist, Reverses Clinically Relevant Inflammatory and Fibrotic Pathways in Chronic Kidney Disease

  1. Sean Eddy
  2. Michelle P. Papadimitriou
  3. Amanda J. Edgley
  4. Robyn G. Langham
  5. Fay L. Khong
  6. Roy C.K. Kong
  7. Simona E. Carbone
  8. Andrew R. Kompa
  9. Yuan Zhang
  10. Alison Cox
  11. Lorna Mitchell
  12. Lalita Subramanian
  13. Sebastian Martini
  14. John Hartman
  15. Felix Eichinger
  16. Bradley Godfrey
  17. Laura H. Mariani
  18. Matthias Kretzler
  19. Darren J. Kelly
  20. the Nephrotic Syndrome Study Network (NEPTUNE)
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Abstract

The authors have withdrawn this manuscript on the basis that key mechanistic conclusions are no longer supported by more recent experiments relating to the antagonistic effect of asengeprast (FT011) of GPR68 signaling. Therefore, the authors do not wish this work to be cited. If you have any questions, please contact the corresponding author.

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  1. Version published to 10.1101/2025.02.21.25322641 on medRxiv