β-Amyloid induces microglial expression of GPC4 and APOE leading to increased neuronal tau pathology and toxicity

  1. Brandon B. Holmes
  2. Thaddeus K. Weigel
  3. Jesseca M. Chung
  4. Sarah K. Kaufman
  5. Brandon I. Apresa
  6. James R. Byrnes
  7. Kaan S. Kumru
  8. Jaime Vaquer-Alicea
  9. Ankit Gupta
  10. Indigo V. L. Rose
  11. Yun Zhang
  12. Alissa L. Nana
  13. Dina Alter
  14. Lea T. Grinberg
  15. Salvatore Spina
  16. Kevin K. Leung
  17. Bruce L. Miller
  18. Carlo Condello
  19. Martin Kampmann
  20. William W. Seeley
  21. Jaeda C. Coutinho-Budd
  22. James A. Wells
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  1. Version published to 10.1186/s13024-025-00883-4
  2. Version published to 10.1101/2025.02.20.637701 on bioRxiv